 | Nadja Katharina Singer University of Vienna Institute of Theoretical Chemistry Währinger Str. 17 1090 Vienna Austria nadja.singer@univie.ac.at +43 1 4277 52766 ORCID: 0000-0001-9938-7900 |
| Focus Area |
| The aim of my project is to use theoretical and computational methods to first, unveil the molecular basis of the absorption and emissive properties of different fluorescent probes, and second, to optimize these properties to efficiently image the activity of neurotransmitter transporters (e.g. dopamine transporter, organic cation transporters 3) and ion channels (e.g. gamma-Aminobutyric acid receptor, GABA_A R). The project will be run within the MolTag framework, where teams from biology to synthetic chemistry interconnect with each other. |
| Awards & Prizes |
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| News |
| Publications |
Molecular Photoswitches Regulating the Activity of the Human Serotonin Transporter (submitted), (2023) N. Singer, L. González, A. Monari PyrAtes: Modular Organic Salts with Large Stokes Shifts for Fluorescence Microscopy (submitted), (2023) 3. N. Singer, K. Schloegl, J. P. Zobel, M. Mihovilovic, L. González Singlet and Triplet Pathways Determine the Thermal Z/E Isomerization of an Arylazopyrazole-Based Photoswitch J. Phys. Chem. Lett. , , (2023), DOI: 10.1021/acs.jpclett.3c01785 2. S. Gómez, N. Singer, L. González, G. Worth Do We need Delocalised Wavefunctions for the Excited State Dynamics of 1,1-Difluoroethylene? Can. J. Chem. 101, 578, (2023), DOI: 10.1139/cjc-2022-0267 This article is part of the special issue: Unravelling the Turn-on Fluorescence Mechanism of a Fluorescein-based Probe in GABAA Receptors Angew. Chem. Int. Ed. 61, e202205198, (2022), DOI: 10.1002/anie.202205198 N. Singer, P. A. Sánchez-Murcia, M. Ernst, L. González N. Singer, P. A. Sánchez-Murcia, M. Ernst, L. González |